atropineˈæ trəˌpin, -pɪn
atropine
English Definitions:
atropine (noun)
a poisonous crystalline alkaloid extracted from the nightshade family; used as an antispasmodic and to dilate the eye pupil; also administered in large amounts as an antidote for organophosphate nerve agents or organophosphate insecticides
atropine (Noun)
An alkaloid extracted from the plant deadly nightshade (Atropa belladonna) and other sources. Though overdoses would be fatal it is used as a drug in medicine for its paralytic effects (e.g. in surgery to relax muscles, in dentistry to dry the mouth, in ophthalmology to dilate the pupils).
Atropine
Atropine is a naturally occurring tropane alkaloid extracted from deadly nightshade, Jimson weed, mandrake and other plants of the family Solanaceae. It is a secondary metabolite of these plants and serves as a drug with a wide variety of effects. In general, atropine counters the "rest and digest" activity of all muscles and glands regulated by the parasympathetic nervous system. This occurs because atropine is a competitive antagonist of the muscarinic acetylcholine receptors. Atropine dilates the pupils, increases heart rate, and reduces salivation and other secretions. Atropine is a core medicine in the World Health Organization's "Essential Drugs List", which is a list of minimum medical needs for a basic health care system.
Atropine
Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate, and to decrease saliva production during surgery. It is typically given intravenously or by injection into a muscle. Eye drops are also available which are used to treat uveitis and early amblyopia. The intravenous solution usually begins working within a minute and lasts half an hour to an hour. Large doses may be required to treat some poisonings.Common side effects include dry mouth, abnormally large pupils, urinary retention, constipation, and a fast heart rate. It should generally not be used in people with closed-angle glaucoma. While there is no evidence that its use during pregnancy causes birth defects, this has not been well studied so sound clinical judgment should be used. It is likely safe during breastfeeding. It is an antimuscarinic (a type of anticholinergic) that works by inhibiting the parasympathetic nervous system.Atropine occurs naturally in a number of plants of the nightshade family, including deadly nightshade (belladonna), Jimson weed, and mandrake. It was first isolated in 1833, It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.
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