acidosisˌæs ɪˈdoʊ sɪs
acidosis (n)
English Definitions:
acidosis (noun)
abnormally high acidity (excess hydrogen-ion concentration) of the blood and other body tissues
acidosis (Noun)
An abnormally increased acidity of the blood.
Acidosis
Acidosis is an increased acidity in the blood and other body tissue. If not further qualified, it usually refers to acidity of the blood plasma. Acidosis is said to occur when arterial pH falls below 7.35, while its counterpart occurs at a pH over 7.45. Arterial blood gas analysis and other tests are required to separate the main causes. The term acidemia describes the state of low blood pH, while acidosis is used to describe the processes leading to these states. Nevertheless, the terms are sometimes used interchangeably. The distinction may be relevant where a patient has factors causing both acidosis and alkalosis, wherein the relative severity of both determines whether the result is a high or a low pH. The rate of cellular metabolic activity affects and, at the same time, is affected by the pH of the body fluids. In mammals, the normal pH of arterial blood lies between 7.35 and 7.50 depending on the species. Blood pH values compatible with life in mammals are limited to a pH range between 6.8 and 7.8. Changes in the pH of arterial blood outside this range result in irreversible cell damage.
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