hemophiliaˌhi məˈfɪl i ə
hemophilia (n)
English Definitions:
hemophilia, haemophilia, bleeder's disease (noun)
congenital tendency to uncontrolled bleeding; usually affects males and is transmitted from mother to son
Hemophilia
A deficiency or abnormality of a blood coagulation factor characterized by the tendency to spontaneous or exaggerated post-traumatic hemorrhage, Hemophilia is typically a hereditary disorder but, rarely, may be acquired. Inherited coagulation factor-deficient hemophilias include hemophilia A or classic hemophilia (Factor VIII deficiency) hemophilia B or Christmas disease (Factor IX deficiency), and hemophilia C (Factor XI deficiency). In individuals without hereditary hemophilia A, Factor VIII inhibitors may occur spontaneously as autoantibodies, resulting in a condition known as 'acquired hemophilia.' Approximately 10 % of patients with acquired hemophilia have an underlying malignancy. --2004
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