spleensplin
spleen (n)
- plural
- spleens
English Definitions:
spleen, lien (noun)
a large dark-red oval organ on the left side of the body between the stomach and the diaphragm; produces cells involved in immune responses
irascibility, short temper, spleen, quick temper (noun)
a feeling of resentful anger
spleen (Noun)
In vertebrates, including humans, a ductless vascular gland, located in the left upper abdomen near the stomach, which destroys old red blood cells, removes debris from the bloodstream, acts as a reservoir of blood, and produces lymphocytes.
spleen (Noun)
A bad mood; spitefulness.
Spleen
The spleen is an organ found in virtually all vertebrate animals. Similar in structure to a large lymph node, it acts primarily as a blood filter. Thus, life is possible after the spleen is removed. The spleen plays important roles in regard to red blood cells and the immune system. It removes old red blood cells and holds a reserve of blood in case of hemorrhagic shock and also recycles iron. As a part of the mononuclear phagocyte system, it metabolizes hemoglobin removed from senescent erythrocytes. The globin portion of hemoglobin is degraded to its constitutive amino acids, and the heme portion is metabolized to bilirubin, which is removed in the liver. The spleen synthesizes antibodies in its white pulp and removes antibody-coated bacteria and antibody-coated blood cells by way of blood and lymph node circulation. A study published in 2009 using mice found that the spleen contains in its reserve half of the body's monocytes within the red pulp. These monocytes, upon moving to injured tissue, turn into dendritic cells and macrophages while promoting tissue healing. The spleen is a center of activity of the reticuloendothelial system and can be considered analogous to a large lymph node, as its absence causes a predisposition to certain infections.
Spleen
The spleen is an organ found in almost all vertebrates. Similar in structure to a large lymph node, it acts primarily as a blood filter. The word spleen comes from Ancient Greek σπλήν (splḗn).The spleen plays very important roles in regard to red blood cells (erythrocytes) and the immune system. It removes old red blood cells and holds a reserve of blood, which can be valuable in case of hemorrhagic shock, and also recycles iron. As a part of the mononuclear phagocyte system, it metabolizes hemoglobin removed from senescent red blood cells. The globin portion of hemoglobin is degraded to its constitutive amino acids, and the heme portion is metabolized to bilirubin, which is removed in the liver.The spleen houses antibody-producing lymphocytes in its white pulp and monocytes which remove antibody-coated bacteria and antibody-coated blood cells by way of blood and lymph node circulation. These monocytes, upon moving to injured tissue (such as the heart after myocardial infarction), turn into dendritic cells and macrophages while promoting tissue healing. The spleen is a center of activity of the mononuclear phagocyte system and is analogous to a large lymph node, as its absence causes a predisposition to certain infections.In humans, the spleen is purple in color and is in the left upper quadrant of the abdomen.
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"spleen." Kamus.net. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.kamus.net/english/spleen>.
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