duedu, dyu
due (n)
- plural
- dues
due (adv)
due
English Definitions:
due (noun)
that which is deserved or owed
"give the devil his due"
due (adj)
a payment that is due (e.g., as the price of membership)
"the society dropped him for non-payment of dues"
due (adj)
owed and payable immediately or on demand
"payment is due"
due(p) (adj)
scheduled to arrive
"the train is due in 15 minutes"
due (adj)
suitable to or expected in the circumstances
"all due respect"; "due cause to honor them"; "a long due promotion"; "in due course"; "due esteem"; "exercising due care"
ascribable, due, imputable, referable (adverb)
capable of being assigned or credited to
"punctuation errors ascribable to careless proofreading"; "the cancellation of the concert was due to the rain"; "the oversight was not imputable to him"
due (adverb)
directly or exactly; straight
"went due North"
due (Noun)
Deserved acknowledgment.
due (Noun)
(in plural dues) A membership fee.
due (Adverb)
Directly; exactly.
due (Adjective)
Owed or owing
due (Adjective)
Appropriate.
due (Adjective)
Scheduled; expected.
due (Adjective)
Having reached the expected, scheduled, or natural time
due
A DNA unwinding element (DUE or DNAUE) is the initiation site for the opening of the double helix structure of the DNA at the origin of replication for DNA synthesis. It is A-T rich and denatures easily due to its low helical stability, which allows the single-strand region to be recognized by origin recognition complex. DUEs are found in both prokaryotic and eukaryotic organisms, but were first discovered in yeast and bacteria origins, by Huang Kowalski. The DNA unwinding allows for access of replication machinery to the newly single strands. In eukaryotes, DUEs are the binding site for DNA-unwinding element binding (DUE-B) proteins required for replication initiation. In prokaryotes, DUEs are found in the form of tandem consensus sequences flanking the 5' end of DnaA binding domain. The act of unwinding at these A-T rich elements occurs even in absence of any origin binding proteins due to negative supercoiling forces, making it an energetically favourable action. DUEs are typically found spanning 30-100 bp of replication origins.
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